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Eye Health
Due to its unique molecular structure, astaxanthin can cross the blood-brain barrier and the blood-retina barrier to reach the eyes, providing protection and supporting eye health as a natural antioxidant supplement.
With many people spending over five hours daily on computers or phone screens, the visual system can gradually weaken, leading to Computer Vision Syndrome. This syndrome may cause eye strain, eye fatigue, dry eyes, blurred vision, and difficulty with eye refocusing, potentially progressing to chronic eye diseases such as cataract, glaucoma, and age-related macular degeneration.
The benefits of astaxanthin for eye health have been confirmed in at least 14 human clinical studies and 24 pre-clinical trials. These findings help explain how astaxanthin promoting vision support and maintains eye health.
This study shows that an intake of 6 mg astaxanthin every day (ET* 1 Astadaily softgel) can improve the eye accommodation rate by 64% in just 4 weeks. (Nitta et al., 2005).
This study shows that astaxanthin can help relieve eye fatigue symptoms in just 4 weeks. (Nagaki et al., 2002).
Supporting Pre-clinical Studies
Besides human clinical studies, there are many pre-clinical studies indicating various benefits of astaxanthin for eye health.
AMD
Astaxanthin protects the vascular layer of the eye in mice and may be a potential therapy for age-related macular degeneration (AMD). In this study, it was found that Astaxanthin can reduce damage caused by abnormal growth of blood vessels in the eyes (a condition that can result in macular degeneration) (Izumi-Nagai et al., 2008).
Cell Protection
Astaxanthin has been shown to reduce high blood pressure in the eyes. Rats with elevated pressure in the retina were fed astaxanthin and were found to have three distinct benefits: reduced inflammation, reduced protein oxidation levels, and perhaps most significant of all, reduced cell death (Cort et al., 2010).
Anti-inflammation
The first study proving astaxanthin’s broad-spectrum anti-inflammatory activity was done on rats’ eyes. The researchers showed that astaxanthin dose dependently reduces three different inflammatory markers (Ohgami et al., 2003).
References
Nitta et al. (2005). Effects of astaxanthin on accommodation and asthenopia-Dose finding study in healthy volunteers. J. Clin. Therap. Med., 21(6):637-650.
Nagaki Y., et al., (2002). Effects of astaxanthin on accommodation, critical flicker fusions, and pattern evoked potential in visual display terminal workers. J. Trad. Med., 19(5):170-173.
Izumi-Nagai, K., Nagai, N., Ohgami, K., Satofuka, S., Ozawa, Y., Tsubota, K., Ohno, S., Oike, Y., Ishida, S. (2008). “Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.” Invest. Opthalmol. Vis. Sci. 49(4):1679-85.
Cort, A., Ozturk, N., Akpinar, D., Unal, M., Yucel, G., Ciftcioglu, A., Yargicoglu, P. Aslan, M. (2010). “Suppressive effect of astaxanthin on retinal injury induced by elevated intraocular pressure.” Regulatory Toxicology and Pharmacology. 58(1):121-30.
Ohgami, K., Shiratori, K., Kotake, S., Nishida, T., Mizuki, N., Yazawa, K., Ohno, S. (2003). “Effects of Astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo.” Investigative Ophthalmology and Visual Science. 44(6):2694-701.
